Symbol
Name
ID

Hes1
hes family bHLH transcription factor 1
MGI:104853

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

abnormal neuron differentiation

abnormal neural tube morphology

everted embryonic neuroepithelium

incomplete rostral neuropore closure

kinked neural tube

increased solitary pulmonary neuroendocrine cell number

abnormal pituitary gland development

pituitary gland hypoplasia

abnormal cochlear hair cell morphology

increased cochlear inner hair cell number

increased cochlear outer hair cell number

increased vestibular hair cell number

abnormal brain development

anencephaly

exencephaly

Availability

Mouse Genotype

Hes1^tm1Fgu/Hes1^tm1Fgu

Hes1^tm2.1Kag/Hes1^tm2.1Kag

Hes1^tm1Fgu/Hes1⁺

Emx1^tm1(cre)Ito/Emx1⁺
Hes1^tm1Kag/Hes1^tm1Kag (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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